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A trial emulation in Nature Medicine shows that treatment with semaglutide and tirzepatide showed similar levels of benefit on cardiovascular outcomes in people at elevated cardiovascular risk with obesity and diabetes. Link
New in the August 14, 2025, issue of NEJM: CagrilintideSemaglutide for Overweight or Obesity (REDEFINE 1 phase 3a trial) Cagrilintide Semaglutide for Overweight and Diabetes (REDEFINE 2 phase 3a trial)
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